United are in Group H along with PSG, Bundesliga side RB Leipzig and Turkish Champions Istanbul Basaksehir in what is being considered the traditional ‘group of death’ for this season.
United’s first test of the Champions League campaign is to travel to the Parc des Princes, the scene of the most unlikely of comebacks in this same competition in 2019.
Marcus Rashford’s stoppage time penalty in Paris ensured United went through at the expense of the French Champions, who held a 2-goal advantage from the first leg at Old Trafford.
PSG reached last season’s Champions League final, though, where they were beaten by Bayern Munich. United meanwhile were knocked out by eventual winners Sevilla in the Europa League last campaign.
The Ligue 1 side have been plagued by injury this week, with several first team stars major doubts for the game.
Juan Bernat definitely misses out with knee ligament damage, but Marquinhos, Marco Verratti, Danilo Pereira, Mauro Icardi, Thilo Kehrer and Julian Draxler are all doubts.
Manager Thomas Tuchel claimed that his side will welcome United with a threadbare squad – no doubt a boost for Ole Gunnar Solskjaer.
The Norwegian though won’t hand Edinson Cavani his debut against his former club, with the deadline day arrival not travelling to the French capital along with United skipper Harry Maguire.
Marcos Rojo and Phil Jones are not likely to feature, but Anthony Martial can play as his Premier League red card doesn’t count for Champions League games – likely leaving Cavani to plug the gap in the Premier League on Saturday.
Mason Greenwood is carrying a knock and it is unknown if he has travelled to Paris. Axel Tuanzebe is with the squad meanwhile as he recovers from injury.
Kick off between United and PSG at the Parc des Princes is 2000 GMT on Tuesday.